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ARICU
by Dr.Atul Rai
Protocol Library
Evidence-based clinical decision support · 144 protocols across 16 categories · 2025–2026 guidelines
All
· 144
General Medicine · ED
· 25
Sepsis & Shock
· 8
Cardiopulmonary & Vent
· 14
Endocrine
· 8
Neurological
· 8
Renal & Metabolic
· 7
Hepatic & GI
· 7
Hematology
· 6
Infection
· 11
Tropical · India
· 13
Obstetric
· 6
Trauma & Burns
· 8
Toxicology
· 8
Care Bundles
· 6
End of Life
· 4
Procedural
· 5
General Medicine · ED
25 protocols
Fever workup · adult
IDSA + ICMR
T > 38 + adult ED arrival
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Acute undifferentiated dyspnea
AAEM 2023
new dyspnea + SpO₂ < 95
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Acute chest pain · HEART score
AHA 2021
chest pain + ED triage
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Acute abdominal pain · workup
WSES 2020
abdominal pain + ED triage
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Acute severe headache · red flags
AHA / NICE
thunderclap | new severe headache
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Renal colic · imaging pathway
EAU / AUA 2024
flank pain + dysuria
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Syncope · risk stratification
ESC 2018
syncope + adult
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Acute decompensated HF · ED
ESC 2021
CHF exacerbation + ED arrival
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Acute confusion · delirium workup
AGS 2014
AMS + adult
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Hypoglycemia · recurrent
Endocrine 2023
recurrent hypoglycemia
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Hyperglycemia · uncomplicated
ADA 2024
BG > 250 + no DKA/HHS
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Acute lower back pain · red flags
NICE 2016
back pain + adult
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Acute hot joint · septic vs gout
ACR 2020
monoarticular swelling
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Acute red eye · vision-threatening
AAO 2021
red eye + ED triage
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Acute severe vertigo · HINTS
AAN 2017
continuous vertigo + adult
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UTI · simple vs complicated
IDSA 2024
UTI symptoms
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Pyelonephritis · severity stratified
IDSA 2024
pyelonephritis dx
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Cellulitis · severity-based
IDSA 2014
cellulitis dx
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Acute viral hepatitis
AASLD
jaundice + transaminitis
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Alcohol withdrawal · CIWA screen
ASAM 2020
withdrawal symptoms
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Hyponatremia · workup pathway
EAES 2014
Na < 130 + adult
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Hypertensive urgency vs emergency
JNC 8
BP > 180/120 + ED
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DVT workup · Wells score
CHEST 2016
unilateral leg swelling
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Falls in elderly · workup
AGS 2010
fall + age > 65
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Anemia · acute evaluation
ASH 2020
Hb < 8 + adult
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Sepsis & Shock
8 protocols
Septic shock · hour-1 bundle
SSC 2026
qSOFA ≥ 2 + lactate > 2
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Severe sepsis · empiric antibiotics
SSC 2021
infection + organ dysfunction
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Vasopressor titration · MAP 65
SSC 2021
MAP < 65 despite fluids
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Refractory septic shock · steroids
ADRENAL / APROCCHSS
norepinephrine > 0.25 mcg/kg/min
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Source control checklist
WSES 2018
sepsis dx confirmed
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Anaphylactic shock
WAO 2020
hypotension + urticaria
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Cardiogenic shock
AHA 2017
SBP < 90 + cold extremities
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Hemorrhagic shock · MTP
ATLS 2018
shock + active bleeding
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Cardiopulmonary & Vent
14 protocols
ARDS · low tidal volume
ESICM 2023
P/F < 300 + bilateral infiltrates
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ARDS · prone positioning
PROSEVA
P/F < 150
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Severe COPD exacerbation · NIV
GOLD 2024
pH < 7.35 + pCO₂ > 45
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Status asthmaticus
GINA 2024
PEF < 33% + silent chest
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Massive PE · thrombolysis
ESC 2019
PE + hemodynamic instability
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STEMI · primary PCI
ACC/AHA 2013
ST elevation + symptoms < 12h
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NSTEMI · early invasive
ESC 2020
rising troponin + GRACE > 140
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Acute pulmonary edema
ESC 2021
SOB + crackles + low SpO₂
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Aortic dissection · type A/B
AHA/ACC 2022
tearing chest/back pain + asymmetric pulses
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New AF · rapid ventricular rate
AHA 2023
new AF + HR > 110
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Vent weaning · SBT protocol
ATS/CHEST
vented > 24h + improving
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Difficult airway · DAS algorithm
DAS 2015
anticipated/failed intubation
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Cardiac arrest · ACLS
AHA 2025
no pulse + no breathing
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Post-arrest care · TTM
AHA 2020
ROSC + comatose
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Endocrine
8 protocols
DKA · fluid + insulin
ADA 2024
BG > 250 + ketones + pH < 7.3
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HHS · slow correction
ADA 2024
BG > 600 + osm > 320
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Severe hypoglycemia
Endocrine 2022
BG < 54 + symptoms
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Thyroid storm
ATA 2016
fever + AF + tremor + hyperthyroid
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Myxedema coma
ATA 2014
hypothermia + AMS + hypothyroid
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Adrenal crisis
Endocrine 2016
shock refractory to fluids/pressors
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Hyperkalemia · acute
KDIGO 2024
K > 6.0 + ECG changes
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Hypercalcemic crisis
Endocrine 2019
Ca > 14 + AMS
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Neurological
8 protocols
Acute ischemic stroke · tPA
AHA 2019
stroke + onset < 4.5h
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Large vessel occlusion · thrombectomy
DAWN/DEFUSE-3
LVO + onset < 24h
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Intracerebral hemorrhage
AHA 2022
CT bleed + neuro deficit
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Subarachnoid hemorrhage
AHA 2023
thunderclap HA + CT/LP positive
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Status epilepticus
NCS 2016
seizure > 5 min
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Bacterial meningitis
IDSA 2017
fever + meningism + AMS
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Acute spinal cord injury
AANS 2013
trauma + paraplegia
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Brain death determination
AAN 2010
GCS 3 + no brainstem reflexes
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Renal & Metabolic
7 protocols
AKI workup · KDIGO
KDIGO 2026
Cr ↑ ≥ 0.3 in 48h
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RRT initiation criteria
KDIGO 2012
AKI + AEIOU criteria
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Rhabdomyolysis
Crit Care 2014
CK > 5000 + dark urine
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Severe metabolic acidosis
ICM 2018
pH < 7.2 + HCO₃ < 15
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Severe hyponatremia
EAES 2014
Na < 120 + symptoms
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Hypernatremia
Endocrine 2018
Na > 155
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Tumor lysis syndrome
BSH 2015
K/PO₄/uric acid ↑ post-chemo
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Hepatic & GI
7 protocols
Acute liver failure
AASLD 2011
INR > 1.5 + encephalopathy
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Variceal bleed · band ligation
AASLD 2017
hematemesis + cirrhosis
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Severe acute pancreatitis
ACG 2013 / ISCCM 2024
BISAP ≥ 3 OR organ failure
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SBP · cirrhosis
AASLD 2021
ascites + PMN > 250
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Hepatic encephalopathy
AASLD 2014
cirrhosis + AMS
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Upper GI bleed · non-variceal
ACG 2021
hematemesis + melena
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Acute mesenteric ischemia
WSES 2017
severe pain + lactate ↑
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Hematology
6 protocols
Massive transfusion protocol
ATLS 2018
ABC ≥ 2 OR shock + bleed
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Reversal · warfarin
ASH 2018
INR > 5 + bleeding
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Reversal · DOAC
ISTH 2021
DOAC + life-threatening bleed
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TTP · plex protocol
ISTH 2020
MAHA + thrombocytopenia
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DIC management
BSH 2009
ISTH score ≥ 5
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HIT workup · 4Ts
ASH 2018
thrombocytopenia + heparin exposure
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Infection
11 protocols
VAP · empiric antibiotics
IDSA 2016
vented > 48h + new infiltrate
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CAUTI workup
IDSA 2010
catheter + fever
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CLABSI workup
IDSA 2009
central line + fever
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Severe CAP · ICU
IDSA/ATS 2019
ATS major criteria met
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Necrotizing fasciitis
IDSA 2014
rapidly spreading + LRINEC ≥ 6
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C. difficile · severe
IDSA/ACG 2021
WBC > 15 + Cr ↑ + CDI+
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Endocarditis · empiric
AHA 2015
fever + new murmur + Duke criteria
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Febrile neutropenia
IDSA 2010
ANC < 500 + T > 38.3
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MDRO de-escalation
ASP 2016
culture sensitivities back
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Severe COVID-19 / viral pneumonitis
NIH 2024
SpO₂ < 94 OR P/F < 300
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Severe acute cholangitis · Tokyo III
Tokyo 2018
Charcot triad + organ failure
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Tropical · India
13 protocols
Severe falciparum malaria
WHO 2023
smear+ + organ dysfunction
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Severe dengue · plasma leak
WHO/NVBDCP 2023
NS1+ + hematocrit rise
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Leptospirosis · Weil's
WHO/CDC
fever + jaundice + AKI
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Scrub typhus
IndianAPI 2015
fever + eschar + hill region
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Snake envenomation · ASV
ICMR 2017
bite + 20WBCT positive
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Cerebral malaria
WHO 2023
severe falciparum + GCS < 11
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Scorpion sting · prazosin
IndianAPI
Indian red scorpion + autonomic storm
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Heat stroke · cold-water immersion
SCCM 2025
core T > 40 + AMS
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Rabies post-exposure
WHO 2018
category III bite
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Tetanus management
WHO 2018
trismus + risus sardonicus
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Enteric fever · severe
IndianAPI 2018
prolonged fever + abdominal signs
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Severe gastroenteritis / cholera
WHO 2017
severe dehydration + diarrhea
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Severe vivax malaria
WHO 2023
vivax+ + organ dysfunction
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Obstetric
6 protocols
Severe pre-eclampsia / eclampsia
ACOG 2020
BP ≥ 160/110 + pregnancy
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Postpartum hemorrhage
FIGO 2022
EBL > 1000 ml post-delivery
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Amniotic fluid embolism
SMFM 2016
sudden hypoxia + collapse intrapartum
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Peripartum cardiomyopathy
ESC 2018
HF in late pregnancy / postpartum
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Sepsis in pregnancy
SOMANZ 2017
qSOFA ≥ 2 + pregnant
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DKA in pregnancy
ACOG 2018
DKA + pregnant (lower BG threshold)
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Trauma & Burns
8 protocols
Polytrauma · ATLS primary
ATLS 2018
trauma activation
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Severe TBI · ICP control
BTF 2016
GCS ≤ 8 + intracranial injury
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Pelvic ring fracture · binder
WSES 2017
unstable pelvis + shock
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Tension pneumothorax
ATLS 2018
shock + tracheal shift
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Cardiac tamponade · trauma
ATLS 2018
Beck's triad + penetrating chest
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Major burns · Parkland
ABA 2023
TBSA > 20% + adult
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Inhalation injury
ABA 2023
burn + closed space + soot
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Crush syndrome
Crit Care 2014
prolonged compression + extrication
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Toxicology
8 protocols
Paracetamol overdose · NAC
AAPCC 2023
acetaminophen ingestion
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Organophosphate poisoning
WHO 2020
muscarinic features + exposure
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Aluminum phosphide poisoning
IndianAPI
AlP ingestion + phosphine breath
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TCA overdose
AAPCC 2018
QRS > 100 + ingestion
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Beta-blocker / CCB overdose
AAPCC 2017
bradycardia + hypotension
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Salicylate poisoning
AAPCC 2015
tinnitus + mixed acid-base
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Methanol / ethylene glycol
AAPCC 2016
high osmolar gap + AGMA
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Opioid overdose · naloxone
WHO 2014
respiratory depression + miosis
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Care Bundles
6 protocols
VAP prevention bundle
IHI 2012
intubated patient
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CLABSI prevention bundle
IHI 2012
central line in situ
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Sedation/analgesia · ABCDEF
SCCM 2018
all ICU patients daily
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DVT prophylaxis
ACCP 2012
ICU admission
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Stress ulcer prophylaxis
SCCM 2020
vented OR coagulopathy
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Glycemic control · ICU
NICE-SUGAR
BG > 180 mg/dL
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End of Life
4 protocols
Withdrawal of life-sustaining therapy
SCCM 2008
futility + family consensus
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Comfort care / palliation
WHO 2018
EoL decision documented
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Family meeting · goals of care
SCCM 2017
prognosis change
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Organ donation referral
WHO 2010
imminent brain death
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Procedural
5 protocols
Central venous access · USG
NICE 2002
vasopressors / RRT planned
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Arterial line insertion
SCCM 2014
shock OR frequent ABG
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Intercostal drain · pneumothorax
BTS 2010
moderate-large pneumothorax
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Lumbar puncture · adult
AAN 2007
meningitis / SAH workup
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Bedside echo · FoCUS
ACEP 2016
shock OR cardiac arrest
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